The following list of products are readily available. Please contact us at enquiries@fluorochem.co.uk or phone 01457 868921 for additional information.
Monoclonal Antibody to PI-3 Kinase
Polyclonal Antibody to Inositol 1,4,5-Triphosphate Receptor Type I
3-Deoxy-3-bromo-Ins(1,4,5)P3. 6Na,
Product Number: D-1107-A
| 1 mg |
3-Deoxy-3-fluoro-d-myo-inositol, 3-F-Ins
Product Number: D-1103-A
Fluorine-substituted analog of myo-inositol that is taken up by cells and incorporated into fluorinated PI. Has antiproliferative effects toward v-sis NIH 3T3 cells and is a possible blocker of synthesis of Ins(1,3,4,5)P4.
| 1 mg |
3-F-Deoxy-Ins(1,4,5)P3. 6Na,
Product Number: D-1109-A
Equal to Ins(1,4,5)P3 in releasing intracellular calcium. The 3-position is blocked by fluorine so it can not be converted to Ins(1,3,4,5)P4 by the action of 3-kinases. Useful for studying the pathways in which InsP3 and InsP4 are closely interactive
| 100 ug |
3-Deoxy-Ins(1,4,5)P3. 6Na, 3-Deoxy-D-myo-inositol 1,4,5-trisphosphate.hexasodium salt
Product Number: D-1105-A
Exhibits very strong ligand binding affinity to the Ins(1,4,5)P3 receptor of bovine adrenal cortex membranes and acts as a strong agonist in releasing calcium from saponin permeabilized SH-Sy5Y human neuroblastoma cells.
| 500 ug |
1-D-3-Deoxy-phosphatidylinositol, DPI; D-3-Deoxy-myo-inositol 1-[(R)-2,3-bis(hexadecanoyloxy)propyl hydrogenphosphate
Product Number: D-1113-A
Antimetabolite of phosphatidylinositol-3-phosphate. An inhibitor of cancer cell colony formation.
| 100 ug |
2,3-Dideoxy-Ins(1,4,5)P3. 6Na, 2,3-dideoxy-d-myo-inositol 1,4,5-trisphosphate.hexasodium salt
Product Number: D-1111-A
Exhibits very strong ligand binding affinity to the Ins(1,4,5)P3 receptor of bovine adrenal cortex membranes and acts as a strong agonist in releasing calcium from saponin permeabilized SH-Sy5Y human neuroblastoma cells.
| 1 mg |
Product Number: I-1060-A
Natural occurring isomer of myo-inositol, product # I-1058.
| 5 mg |
myo-Inositol,
Product Number: I-1058-A
| 25 g |
Polyclonal Antibody to Inositol 1,4,5-Triphosphate Receptor Type I, Rabbit Polyclonal Antibody. Immunogen: Human IP3R-I (1829-1848) peptide sequence. Specificity: Recognizes ~240 kDa IP3 receptor type I in human, dog, and rat. Application: WB 1/1000, IH 1/100.
Product Number: I-1064-A
| 100 ul |
L-myo-Inositol 1,4,5-trisphosphate.6K, L-myo-Inositol 1,4,5-trisphosphate.6K
Product Number: I-1038-A
Inactive negative control for D-myo-Inositol 1,4,5-trisphosphate.
| 1 mg |
DL-myo-Inositol 1,5-bisphosphate.dipotassium salt, DL-myo-Inositol 1,5-bisphosphate.dipotassium salt
Product Number: I-1046-A
| 100 ug |
D-myo-Inositol 1-phosphate.dipotassium salt, D-myo-Inositol 1-phosphate.dipotassium salt
Product Number: I-1042-A
| 1 mg |
DL-myo-Inositol 3,4,5,6-tetrakisphosphate.tetrapotassium salt, D-myo-Inositol 3,4,5,6-tetrakisphosphate.tetrapotassium salt
Product Number: I-1056-A
| 100 ug |
Ins(1,2,3,4)P4. 4K, D-myo-Inositol 1,2,3,4-tetrakisphosphate.4K
Product Number: I-1068-A
| 100 ug |
Ins(1,2,3,5)P4. 4K, D-myo-Inositol 1,2,3,5-pentaphosphate.pentapotassium salt
Product Number: I-1052-A
| 100 ug |
Ins(1,2,3,6)P4. 4K, D-myo-Inositol 1,2,3,6-Tetrakisphosphate.4K
Product Number: I-1070-A
| 100 ug |
Ins(1,2,5,6)P4, D-myo-Inositol 1,2,5,6-tetraphosphate, potassium salt
Product Number: P-1109-A
| 100 ug |
Ins(1,3,4)P3, D-myo-Inositol 1,3,4-trisphosphate.potassium salt, synthetic
Product Number: D-1023-A
Produced upon hormonal stimulation of cells.
| 100 ug |
Ins(1,3,4,5)P4, D-myo-inositol 1,3,4,5-tetrakisphosphate.octapotassium salt, synthetic
Product Number: D-1025-A
Suggested to play a second-messenger role different from that of Ins(1,4,5)P3.
| 100 ug |
Ins(1,3,4,5,6)P5. 5K, myo-Inositol 1,3,4,5,6-pentakisphosphate.pentapotassium salt
Product Number: I-1054-A
| 100 ug |
Ins(1,3,4,6)P4, D-myo-Inositol 1,3,4,6-trisphosphate., potassium
Product Number: P-1113-A
| 100 ug |
Ins(1,3,5,6)P4. 4K, D-myo-Inositol 1,3,5,6-tetrakisphosphate.tetrapotassium salt
Product Number: I-1050-A
| 100 ug |
Ins(1,4,5)P3, IP3, D-myo-Inositol 1,4,5-trisphosphate.hexapotassium salt, synthetic
Product Number: D-1021-A
Causes release of calcium from intracellular stores.
| 1 mg |
Ins(1,4,5)P3. 3 Li, D-myo-Inositol 1,4,5-trisphosphate.trilithium salt
Product Number: D-1097-A
Causes release of calcium from intracellular stores. Trilithium Salt Form.
| 1 mg |
Ins(1,4,5)P3. 3NH3, D-myo-Inositol 1,4,5 trisphosphate.triammonium salt
Product Number: D-1101-A
Causes release of calcium from intracellular stores. Ammonium Salt Form.
| 1 mg |
Ins(1,4,5)P3. 6 Na, D-myo-Inositol 1,4,5 trisphosphate.trilithium salt
Product Number: D-1099-A
Causes release of calcium from intracellular stores. Sodium Salt Form.
| 1 mg |
Ins(1,4,5,6)P4, D-myo-Inositol 1,4,5,6-tetraphosphate, potassium salt
Product Number: P-1107-A
| 100 ug |
Ins(1,4,6)P3. 3 K, D-myo-Inositol 1,4,6-trisphosphate.tripotassium salt
Product Number: I-1048-A
| 100 ug |
Ins(1,4,6)P3. 3K, D-myo-Inositol 1,4,6-trisphosphate.tripotassium salt
Product Number: I-1048-A
| 100 ug |
Ins(1,5)P2. 4K, D-myo-Inositol 1,5-bisphosphate.tetrapotassium salt
Product Number: I-1044-A
| 100 ug |
Ins(1,5,6)P3, D-myo-Inositol 1,5,6-trisphosphate, potassium salt
Product Number: P-1105-A
| 100 ug |
Ins(2,3,5)P3. 3K, D-myo-Inositol 2,3,5-trisphosphate.tripotassium salt
Product Number: I-1048-A
| 100 ug |
Ins(3,4,5)P3.3K, D-myo-Inositol 3,4,5-trisphosphate, 3K
Product Number: I-1066-A
| 100 ug |
Ins(3,4,5,6)P4, D-myo-Inositol 3,4,5,6-tetraphosphate, potassium salt
Product Number: P-1111-A
| 100 ug |
IRS-1 (Y608) Peptide, Lys-Lys-His-Thr-Asp-Asp-Gly-Tyr-Met-Pro-Met-Ser-Pro-Gly-Val-Ala
Product Number: I-1062-A
The tyrosine phosphorylated version of this peptide binds to phosphatidylinositol 3-kinase SH2 domain and activates the enzyme.
| 1 mg |
KY12420, Wortmannin, Penicillium wortmanni,
Product Number: W-1022-A
A fungal metabolite that specifically inhibits phosphatidylinositol 3-kinase (PI-3), mitogen-activated protein kinase (MAPK) and myosin light-chain kinase (MLCK).
| 5 mg |
LY-294002, 2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one
Product Number: L-1023-A
A potent and specific, cell permeable inhibitor of phosphatidylinositol 3-kinase (PI3-Kinase).
| 5 mg |
Phosphatidylinositol 3-Kinase SH3 Domain Binding Peptide, PI3K SH3.Trifluoroacetate salt, H-Arg-Lys-Leu-Pro-Pro-Arg-Pro-Arg-Arg-NH2
Product Number: P-1143-A
Selectively binds to PI3K SH3 (Km=7.6 um).
| 1 mg |
Phosphatidylinositol-3,4,5-trisphosphate, PtdIns(3,4,5)P3, [1-0-Stearoyl-2-0-arachidonoyl-sn-glycer-3-yl-D-myo-inositol-3,4,5-trisphosphate.tetraammonium salt
Product Number: P-1035-A
Identical to naturally occurring PtdIns(3,4,)P3. It is not an analog containing only saturated fatty acid residues. This material has been found to display significantly greater biological activity [3,4] than such saturated analogs.
| 100 ug |
PI(3)P, di C16, L-a-D-myo-Phosphatidylinositol 3-monophosphate
Product Number: P-1133-A
Natural occurring form. Substrate for PIP4K a and b .
| 100 ug |
PI(3)P, di C8, L-a-D-myo-Phosphatidylinositol 3-monophosphate
Product Number: P-1131-A
Water soluble form. Substrate for PIP4K a and b .
| 100 ug |
PI(3,4)P2, di C16, L-a-D-myo-Phosphatidylinositol 3,4-diphosphate
Product Number: P-1121-A
Natural occurring form. Substrate for PIP5K. Inhibited by PI(4,5)P2.
| 100 ug |
PI(3,4)P2, di C8, L-a-D-myo-Phosphatidylinositol 3,4-diphosphate
Product Number: P-1119-A
Water soluble form. Substrate for PIP5K. Inhibited by PI(4,5)P2.
| 100 ug |
PI(3,4,5)P3, di C16, L-a-D-myo-Phosphatidylinositol 3,4,5-diphosphate
Product Number: P-1129-A
Natural occurring form.
| 100 ug |
PI(3,4,5)P3, di C8, L-a-D-myo-Phosphatidylinositol 3,4,5-diphosphate
Product Number: P-1127-A
Water soluble form.
| 100 ug |
PI(3,5)P2, di C16, L-a-D-myo-Phosphatidylinositol 3,5-diphosphate
Product Number: P-1125-A
Natural occurring form.
| 100 ug |
PI(3,5)P2, di C8, L-a-D-myo-Phosphatidylinositol 3,5-diphosphate
Product Number: P-1123-A
Water soluble form.
| 100 ug |
PI(4)P, di C16, L-a-D-myo-Phosphatidylinositol 4-monophosphate
Product Number: P-1137-A
Natural occurring form. Substrate for PIP5K and PI3K (Class IA, IB, II).
| 100 ug |
PI(4)P, di C8, L-a-D-myo-Phosphatidylinositol 4-monophosphate
Product Number: P-1135-A
Water soluble form. Substrate for PIP5K and PI3K (Class IA, IB, II).
| 100 ug |
PI(4,5)P2, di C16, L-a-D-myo-Phosphatidylinositol 4,5-diphosphate
Product Number: P-1117-A
Natural occurring form. Substrate for PI3K (Class IA, IB, II).
| 500 ug |
PI(4,5)P2,di C8, L-a-D-myo-Phosphatidylinositol 4,5-diphosphate
Product Number: P-1115-A
Water soluble form. Substrate for PI3K (Class IA, IB, II).
| 500 ug |
PI(5), di C16, L-a-D-myo-Phosphatidylinositol 5-monophosphate
Product Number: P-1141-A
Natural occurring form. Substrate for PIP4K a and b . Inhibited by PI(4,5)P2.
| 100 ug |
PI(5), di C8, L-a-D-myo-Phosphatidylinositol 5-monophosphate
Product Number: P-1139-A
Water soluble form. Substrate for PIP4K a and b . Inhibited by PI(4,5)P2.
| 100 ug |
Monoclonal Antibody to PI-3 Kinase, human, recombinant (mouse), Clone: AB6, Isotype: Mouse, IgG1k . Application: Western blot, Immunocytochemistry, Immunoprecipitation, Cross Reactivity with other species has not been determined, Immunogen: recombinant human p85a expressed in E. coli.
Product Number: P-1145-A
Reacts with p85a which is the regulatory subunit of PI 3-kinase. Does not react with p85b .
| 100 mg |
Polyclonal Antibody to Inositol 1,4,5-Triphosphate Receptor Type I, Rabbit Polyclonal Antibody. Immunogen: Human IP3R-I (1829-1848) peptide sequence. Specificity: Recognizes ~240 kDa IP3 receptor type I in human, dog, and rat. Application: WB 1/1000, IH 1/100.
Product Number: I-1064-A
| 100 ul |
L-Quebrachitol, 1L-2-O-Methyl-chiro-inositol
Product Number: Q-1002-A
Key starting material for synthesis of optically active inositol phosphates.
| 1 g |
2,3,6-Trideoxy-Ins(1,4,5)P3. 6Na, 2,3,6-Trideoxy-d-myo-inositol 1,4,5-trisphosphate.hexasodium salt
Product Number: T-1028-A
Exhibits relatively low ligand binding affinity to the Ins(1,4,5)P3 receptor of bovine adrenal cortex membranes and acts as a weak agonist in releasing calcium from saponin permeablized SH-Sy5Y human neuroblastoma cells.
| 1 mg |
Wortmannin, Penicillium wortmanni, KY12420
Product Number: W-1022-A
A fungal metabolite that specifically inhibits phosphatidylinositol 3-kinase (PI-3), mitogen-activated protein kinase (MAPK) and myosin light-chain kinase (MLCK).
| 5 mg |
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